Clinical Significance

Amylase is an enzymes from pancreatic or salivary origin that hydrolyses 1, 4 –a-glucosidic bonds, thus helping for starch digestion, Analysis of serum amylase is mainly used in the diagnosis of the pancreatic diseases (acute or chronic pancreatitis and their complications , carcinoma) During acute pancreatitis, a transitory increase of serum amylase is observed, a peak being reached approximately 12 h after the beginning, the activity returning to the normal after 3 or 4 days. However, a serum amylase increase is also observed in other intra-abdominal pathologies, over or lung cancers, salivary gland lesions, acute alcoholism, renal insufficiency or macroaylasemia (presence of a complex amylase –IgG not filtered by the glomerulus).

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