GAMMA GT PLUS SL
Gamma-glutamyltransferase (GGT) is a membrane-localized peptidase mainly present in kidneys, pancreas, liver and prosta- te. This enzyme plays a significant role in glutathione metabo- lism and takes part in the transport of amino acids into the cells. The rise of GGT activity, often isolated (earlier and longer increa- se compared to other enzymes), is one of the most sensitive indicators of an affection of the liver or bile ducts. The strongest increases are observed in cases of intrahepatic or posthepatic biliary obstructions (reaching levels from 5 to 30 times normal), primary or secondary neoplasms, acute or chronic pancreatitis, and other pancreatic malignancies (especially those associated with hepatobiliary obstruction). More moderate elevations are observed during infectious hepatitis, cirrhosis and hepatic stea- tosis. Alcohol in chronic ingestion, some drugs like phenobarbi- tal and phenytoine or contraceptives can also increase GGT rate in the serum.